This course consists of three modules:
1st module Introduction to structural biology: Introduction to the world of structural biology, with a focus on its importance for understanding the function of biomolecules. Students will become familiar with the use of synchrotron radiation and will have the opportunity to study real experimental data from the European Center for Synchrotron Radiation (ESRF), learning how these are converted into three-dimensional imaging and models of biomolecules. The module combines theory, data analysis, and practical modeling of three-dimensional protein structures.
2nd module: Biomaterials for tissue regeneration and tissue engineering applications: Emphasis is given on ceramics, polymers, composites, nanoparticles, implants and scaffolds for hard and soft tissue replacement and regeneration.
3rd module: Biosensors: Some basic concepts for biosensors (limit of detection LOD, limit of quantification LOQ, ROC curve), the different ways of biorecognition of detection target molecules (antibodies, aptamers, enzymes) and the physical and chemical methods used for detection will be presented: optical methods (absorption, fluorescence/luminescence, plasmon surface effect, SERS), mechanical and electrochemical methods, as well as nanopores.